Thyroid gland

Thyroid

Location: Base of larynx

Hormones:

(i) Thyroxine
(ii) Triodothronine (Both are iodinated amino acids)

Functions: Regulate cellular oxidation of food and basal metabolism, growth differentiation

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Effect of hyposecretion


Cretinism in children, and Myxodema in adult.
Iodine deficiency goiter.
Hashimoto Disease: It occurs in middle aged females due to sensitization of their
own thyroid protein called thyroglobulin. There is mild hypothyroidism. The thyroid gland is enlarged.


Effect of Hypersecretion:

Exophthalamic goiter/ Grave disease indicated by protruding eyes, loss of weight, nervous- ness and fast heart beat.

(iv) Calcitonin (Protein): Regulates calcium and phosphorus


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